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DynaFit 4.04.061 Beta
Kinetic data fitting with reaction modelsDynaFit fits chemical kinetic, enzyme kinetic and ligand-receptor binding data using nonlinear least-squares regression. It works with initial reaction velocities measured against changing species concentrations, as well as reaction progress curves such as absorbance over time. Researchers define reaction schemes with symbolic, stoichiometric equations, assign arbitrary names to species and use the model to estimate kinetic parameters.
DynaFit 4.04.061 Beta details
| Author: | BioKin, Ltd. |
| License: | Freeware |
| Price: | FREE |
| Released: | Oct 11, 2010 |
| File size: | 5.80 MB |
| Downloads: | 304 |
| Keywords: | chemical, Windows 10 compatible, enzyme kinetic, DynaFit software, chemical analysis, data analysis tool, enzyme, ligand receptor binding analysis, reaction progress curve fitting, BioKin Ltd, biochemical kinetics, enzyme inhibition modeling, kinetic, x64 architecture, chemical kinetics software, nonlinear regression kinetics, enzyme kinetics analysis, chemical kinetic |
| Author URL: | http://www.biokin.com/ |
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DynaFit for Windows 10 - Full description
DynaFit is a scientific analysis program for researchers working with chemical kinetics, enzyme kinetics and ligand-receptor binding. It fits experimental measurements to kinetic models using nonlinear least-squares regression, helping investigators estimate model parameters and assess how well a proposed reaction scheme accounts for observed data.
The software accepts initial reaction velocities measured as concentrations of selected species vary, such as inhibitor concentration versus reaction velocity. It can also analyze reaction progress curves, including measurements such as absorbance over time. These different data types let researchers study both steady-state behavior and changes as a reaction proceeds, using a model suited to the experiment.
A central part of DynaFit's workflow is expressing the reacting system as symbolic, stoichiometric equations. Investigators define species and describe their transformations and rate constants, then use that scheme as the basis for fitting the experimental data. Species names are chosen by the user, so models can use terms appropriate to a particular enzyme, substrate, inhibitor or other component. This makes the input readable as a reaction network rather than requiring species to be represented only by opaque labels.
The approach is useful for examining enzyme inhibition, substrate conversion and binding interactions, as well as other systems that can be represented by chemical reaction steps. For example, a model can represent enzyme association, inhibitor binding, substrate reaction and product formation as separate processes. Comparing fitted models with measurements can support the investigation of competing kinetic explanations and the estimation of their rate constants.
DynaFit is freeware from BioKin, Ltd. Its data-fitting capabilities are intended for scientific analysis rather than general spreadsheet work, and useful results depend on selecting a chemically meaningful model and supplying suitable experimental measurements. The supplied compatibility information covers older Windows releases through Windows 8; it does not establish support for Windows 10 or Windows 11.